​گروه پژوهش و مطالعات بالینی 

Clinical Research & Study Group

Determining the Upgrade Rate of De-novo Breast Intraductal Papillomas to Malignancy, its Related Risk Factors, and 6-Month Outcome After Treatment

Determining the Upgrade Rate of De-novo Breast Intraductal Papillomas to Malignancy, its Related Risk Factors, and 6-Month Outcome After Treatment
  نام ژورنال Indian Journal of Surgical Oncology سال پابلیش 22 April 2025 ایمپکت فکتور / Impact Factor 0.7 چهارک مجله / Journal Quartile 3 نوع پابلیش ژورنال / Type of Publication Closed Access / ناشر مجله  Publisher Springer کشور India نوع مقاله Original Article  
ادامه مطلب

Clinical and Demographic Correlates of MRSA and mecA-Positive Isolates in a Tertiary Hospital, Tehran: A Cross-Sectional Study.

Clinical and Demographic Correlates of MRSA and mecA-Positive Isolates in a Tertiary Hospital, Tehran: A Cross-Sectional Study.
  Abstract Background: Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of healthcareassociated infections, with the mecA gene serving as a key marker of resistance. This study investigates the clinical and demographic factors associated with MRSA and mecA carriage in a tertiary hospital in Tehran to inform targeted infection control strategies.. Methods: This cross-sectional study included 125 hospitalized patients with Staphylococcus aureus infections from a tertiary hospital in Tehran. Clinical …
ادامه مطلب

Simultaneous Investigation: Streptococcus pyogenes and Molecular COVID-19 Testing in Corona Suspected Cases

Simultaneous Investigation: Streptococcus pyogenes and Molecular COVID-19 Testing in Corona Suspected Cases
Abstract Background The relationship between Streptococcus pyogenes (Group A Streptococcus) and COVID-19 has been of interest because of possible coinfections and their clinical implications. This discussion examines the interaction between these pathogens and focuses on rates of coinfection, effects, and diagnostic considerations. Materials and Methods This study on 119 COVID-19 patients involved sampling pharyngeal and nasal secretions for streptococcal culture and PCR testing. RNA extraction, cDNA synthesis, and RT-qPCR targeted …
ادامه مطلب

Clinical and Demographic Correlates of MRSA and mecA-Positive Isolates in a Tertiary Hospital, Tehran: A Cross-Sectional Study

Clinical and Demographic Correlates of MRSA and mecA-Positive Isolates in a Tertiary Hospital, Tehran: A Cross-Sectional Study
ABSTRACT Background: Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of healthcare associated infections, with the mecA gene serving as a key marker of resistance. This study investigates the clinical and demographic factors associated with MRSA and mecA carriage in a tertiary hospital in Tehran to inform targeted infection control strategies.. Methods: This cross-sectional study included 125 hospitalized patients with Staphylococcus aureus infections from a tertiary hospital in Tehran. Clinical …
ادامه مطلب

Clinical and Demographic Correlates of MRSA and mecA-Positive Isolates in a Tertiary Hospital, Tehran: A Cross-Sectional Study

Clinical and Demographic Correlates of MRSA and mecA-Positive Isolates in a Tertiary Hospital, Tehran: A Cross-Sectional Study
Abstract Background:   Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of healthcare-associated infections, with the mecA gene serving as a key marker of resistance. This study investigates the clinical and demographic factors associated with MRSA and mecA carriage in a tertiary hospital in Tehran to inform targeted infection control strategies.. Methods:   This cross-sectional study included 125 hospitalized patients with Staphylococcus aureus infections from a tertiary hospital in Tehran. Clinical and …
ادامه مطلب

Emotional alexithymia as a mediator between body image concerns and marital quality of life in post-mastectomy breast cancer patients.

 Emotional alexithymia as a mediator between body image concerns and marital quality of life in post-mastectomy breast cancer patients.
Abstract Background: Breast cancer often requires mastectomy, leading to psychological distress and reduced quality of life. Objectives: This study examined the mediating role of alexithymia, specifically its 3 dimensions, in the relationship between body image concerns and marital quality of life in post-mastectomy patients. Methods: This cross-sectional study enrolled 120 married women (aged 20 - 50) with stage I - II breast cancer who had undergone mastectomy at Shohada Tajrish …
ادامه مطلب

Unveiling Diagnostic Significance: Exploring miR-21, IL-12, and INF-Y in Various Breast Cancer Stages and Grades

Unveiling Diagnostic Significance: Exploring miR-21, IL-12, and INF-Y in Various Breast Cancer Stages and Grades
Abstract Studying miR-21, IL-12, and INF-Y as diagnostic markers in breast cancer stages aids in early detection and optimizing treatment for improved patient outcomes. In the current research, 150 breast cancer patients and 50 healthy controls from Baqiyatullah and Shahada Hospital underwent ELISA for IL-12 and INF-Y and real-time PCR for miR-21 expression. We examined 150 patients with BC and 50 healthy individuals. The average age was 51.56 ± 10.16 years. 96.5% …
ادامه مطلب

Molecular profiling of human Papillomavirus (HPV) genotypes in Iranian women with atypical squamous cells of undetermined significance (ASCUS) cytology: predominance of high-risk types linked to cervical cancer risk.

Molecular profiling of human Papillomavirus (HPV) genotypes in Iranian women with atypical squamous cells of undetermined significance (ASCUS) cytology: predominance of high-risk types linked to cervical cancer risk.
Abstract Background: Human papillomavirus (HPV) is a common sexually transmitted infection and a major cause of cervical cancer, which is a leading cause of cancer-related death among women worldwide. Objectives: This study aimed to molecularly profile HPV genotypes in Iranian women with atypical squamous cells of undetermined significance (ASCUS) on cytology using real-time polymerase chain reaction (PCR) to improve viral detection, genotype characterization, risk stratification, and clinical management. Methods: A …
ادامه مطلب

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